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Wnt/Stem Cell

Chemical Structure Cat. No. Product Name CAS No.
A-3 Hydrochloride Chemical Structure
BCP37347 A-3 Hydrochloride 78957-85-4
A-3 hydrochloride is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.
BRD0705 Chemical Structure
BCP33275 BRD0705 2056261-41-5
BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor. BRD0705 can be used for acute myeloid leukemia.
Adavivint Chemical Structure
BCP36799 Adavivint 1467013-03-3
Adavivint is a Wnt pathway inhibitor.
CB-103 Chemical Structure
BCP36784 CB-103 218457-67-1
CB-103 is a first-in-class orally active notch signaling pathway inhibitor extracted from patent US9296682B2.
Deuruxolitinib Chemical Structure
BCP36774 Deuruxolitinib 1513883-39-0
NRX-252262 Chemical Structure
BCP36626 NRX-252262 2438637-61-5
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM.
ZLDI-8 Chemical Structure
BCP36163 ZLDI-8 667880-38-8
ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor.
AZD-4205 Chemical Structure
BCP36112 AZD-4205 2091134-68-6
AZD4205 is a novel potent and selective janus kinase 1 (JAK1) inhibitor.
MSAB Chemical Structure
BCP35746 MSAB 173436-66-3
MSAB is a selective inhibitor of Wnt/β-catenin signaling.
Gusacitinib hydrochloride Chemical Structure
BCP35707 Gusacitinib hydrochloride 2228989-14-6
Gusacitinib (ASN-002) is an orally active and potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM.
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