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TLR

Chemical Structure Cat. No. Product Name CAS No.
Pam3CSK4 Chemical Structure
 BCP35467 Pam3CSK4 112208-00-1
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2.
Selgantolimod Chemical Structure
 BCP35099 Selgantolimod 2004677-13-6
Selgantolimod is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection.
AN3485 Hydrochloride Chemical Structure
 BCP34877 AN3485 Hydrochloride 1213786-72-1
AN3485 Hydrochloride is an inhibitor of TLR2-, TLR3-, TLR4- and TLR5-mediated TNF-α, IL-1β and IL-6.
AN-3485 Chemical Structure
 BCP34878 AN-3485 1213827-99-6
AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM.
IAXO-102 Chemical Structure
 BCP34881 IAXO-102 1115270-63-7
IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling.
TLR7/8 agonist Chemical Structure
 BCP34811 TLR7/8 agonist 210304-20-4
Loxoribine Chemical Structure
 BCP33260 Loxoribine 121288-39-9
Loxoribine is a potent new immunostimulant with a relatively broad spectrum of immunobiological activities.
TLR4-IN-C34 Chemical Structure
 BCP33213 TLR4-IN-C34 40592-88-9
TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis.
MD2-TLR4-IN-1 Chemical Structure
 BCP32678 MD2-TLR4-IN-1 2249801-12-3
MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively.
Chloroquine diphosphate Chemical Structure
 BCP31956 Chloroquine diphosphate 50-63-5
Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis.
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