Classified by application
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Signaling Pathways
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- Epigenetics
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GPCR/G Protein
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Neuro Signaling Pathway
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Protease/Metabolic Enzyme
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Research Areas
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Azaindazole
- Pyridazine Series
- Nucleoside Series
- Quinoline Series
- Quinazoline
- Pyrazole Series
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- Indole Series
- Azaindole
- Piperidine Series
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- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
TAM Receptor
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP35046 | RU-301 New | 1110873-99-8 |
RU-301 is a novel pan-tam inhibitor, blocking the interface between tam ig1 ectodomain and gas6 lg domain, potently inhibiting axl reporter cell lines and native tam receptors cancer cell lines.
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BCP34892 | TAM-IN-2 New | 2135642-56-5 |
TAM-IN-2 is a TAM inhibitor extracted from patent US 20170275290 A1, pyrrolotriazine compound 0904.
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BCP33929 | UNC2541 New | 1612782-86-1 |
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
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BCP33232 | ONO7475 New | 1646839-59-9 |
ONO-7475 is a potent and orally active Axl/Mer inhibitor. ONO-7475 targets and binds to both Axl and Mer, and prevents their activity.
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BCP13190 | BMS 777607 New | 1196681-44-3 |
BMS 777607 is a novel, selective and orally available ATP-competitive MET kinase inhibitor that primarily targets several MET family members, including RON, MET, Tyro-3 and AxI, with half maximal inhibitory concentration IC50 of 1.8 nmol/L, 3.9 nmol/L, 4.3 nmol/L and 1.1 nmol/L respectively.
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BCP29576 | S49076 HCl New | 1265966-31-1 |
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo.
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BCP27888 | UNC1062 | 1350549-36-8 |
UNC1062 is a novel MERTK-selective tyrosine kinase inhibitor
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BCP27883 | UNC569 | 1350547-65-7 |
UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.
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BCP16544 | UNC2025 | 1429881-91-3 |
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
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BCP29099 | Sitravatinib | 1123837-84-2 |
Sitravatinib (MGCD516,MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.
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