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STING

Chemical Structure Cat. No. Product Name CAS No.
MSA-2 Chemical Structure
BCP35448 MSA-2 129425-81-6
MSA-2 is an orally available non-nucleotide STING agonist, with EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.
SR-717 free acid Chemical Structure
BCP35922 SR-717 free acid 2375420-34-9
SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 free acid is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity.
SR-717 Chemical Structure
BCP35417 SR-717 2375421-09-1
SR-717 is an agonist of stimulator of interferon genes STING for treating cancer.
Omaveloxolone Chemical Structure
BCP28609 Omaveloxolone 1474034-05-3
Omaveloxolone, also known as RTA-408, is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity.
diABZI STING agonist-1 Chemical Structure
BCP33343 diABZI STING agonist-1 2138299-33-7
diABZI STING agonist-1 is a potent non-nucleotide STING agonist and has tremendous potential to improve treatment of cancer in humans.
STING agonist-1 Chemical Structure
BCP33022 STING agonist-1 702662-50-8
STING agonist-1 (G10) is a human-specific STING agonist, triggering IRF3/IFN-associated transcription in human fibroblasts.
ADUS100 sodium Chemical Structure
BCP29778 ADUS100 sodium 1638750-95-4
ADU-S100 is a Cyclic Dinucleotide Agonist of STING (Stimulator of Interferon Genes) pathway.
diABZI STING agonist-1 Chemical Structure
BCP29981 diABZI STING agonist-1 2138498-18-5
diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
(3-Chlorophenyl)hydrazonomalononitrile Chemical Structure
BCP31475 (3-Chlorophenyl)hydrazonomalononitrile 555-60-2
CCCP is a nitrile, a hydrazone and a member of monochlorobenzenes. It derives from a hydrazonomalononitrile.
C-178 Chemical Structure
BCP31292 C-178 329198-87-0?
C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING; covalently binds to Cys91, directly targets mouse STING (mmSTING) but not human STING (hsSTING).
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