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Sodium Channel

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Sodium Channel

Chemical Structure Cat. No. Product Name CAS No.
Licarbazepine Chemical Structure
 BCP35919 Licarbazepine 29331-92-8
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. It is an active metabolite of oxcarbazepine. In addition, an isomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate. Oxcarbazepine and eslicarbazepine acetate are inactive on their own, and behave instead as prodrugs to licarbazepine and eslicarbazepine, respectively, to produce their therapeutic effects.
Oxcarbazepine Chemical Structure
 BCP33398 Oxcarbazepine 28721-07-5
Oxcarbazepine is a sodium channel protein inhibitor.
Lidocaine N-ethyl bromide Chemical Structure
 BCP33056 Lidocaine N-ethyl bromide 21306-56-9
Lidocaine N-ethyl bromide is a membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na+ channels.
QX-314 chloride Chemical Structure
 BCP33036 QX-314 chloride 5369-03-9
QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker.
BI 01383298 Chemical Structure
 BCP32582 BI 01383298 2227549-00-8
BI01383298 is a potent inhibitor of SLC13A5, being selective over other family members and other transporters.
Eleclazine Hydrochloride Chemical Structure
 BCP32600 Eleclazine Hydrochloride 1448754-43-5
Eleclazine hydrochloride is a novel late Na+ current inhibitor.
Eleclazine Chemical Structure
 BCP32599 Eleclazine 1443211-72-0
Eleclazine has been used in trials studying the treatment of LQT2 Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, among others.
Amitriptyline hydrochloride Chemical Structure
 BCP31573 Amitriptyline hydrochloride 549-18-8
Amitriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).
Sipatrigine Chemical Structure
 BCP31183 Sipatrigine 130800-90-7
Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke.
PF-06869206 Chemical Structure
 BCP31135 PF-06869206 2227425-05-8
PF-06869206 is an orally bioavailable selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with an IC50 of 380 nM.
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