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Sirtuin

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Sirtuin

Chemical Structure Cat. No. Product Name CAS No.
SRT2183 Chemical Structure
 BCP37408 SRT2183 1001908-89-9
SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.
CAY10602 Chemical Structure
 BCP32626 CAY10602 374922-43-7
CAY10602 is a SIRT1 activator.
DMNQ Chemical Structure
 BCP31298 DMNQ 6956-96-3
DMNQ is a superoxide generating agent. DMNQ mimicks high glucose-suppressed SIRT2 and SIRT6 expression.
Acetyl-trans-resveratrol Chemical Structure
 BCP24098 Acetyl-trans-resveratrol 42206-94-0
Triacetyl resveratrol is Resveratrol prodrug.
Cambinol Chemical Structure
 BCP28973 Cambinol 14513-15-6
Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively.
OSS128167 Chemical Structure
 BCP28960 OSS128167 887686-02-4
OSS-128167, also known as SIRT6-IN-1, is a potent and selective SIRT 6 inhibitor.
Sirtinol Chemical Structure
 BCP22454 Sirtinol 410536-97-9
Sirtinol is a sirtuin inhibitor, with IC50s of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively.
Resveratrol Chemical Structure
 BCP01416 Resveratrol 501-36-0
Resveratrol is a phenolic phytoalexin found in grape skin and other plants.
SRT 1720 Chemical Structure
 BCP13176 SRT 1720 925434-55-5
SRT 1720 is a selective activator of human SIRT1 with an EC1.5 of 0.16 μM, and shows less potent activities agaiinst SIRT2 and SIRT3 with EC1.5s of 37 μM and > 300 μM, respectively.
AK-1 Chemical Structure
 BCP09326 AK-1 330461-64-8
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor.
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