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Chemical Structure Cat. No. Product Name CAS No.
beta-Elemene Chemical Structure
BCP31326 beta-Elemene 33880-83-0
beta-Elemene is an inhibitor of Pak1 activation, and an anti-cancer ingredient isolated from the Chinese traditional herb Curcuma wenyujin.
FTY720 Acetic Acid Hydrochloride Chemical Structure
BCP31238 FTY720 Acetic Acid Hydrochloride 1346598-36-4
FTY720 is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.
KPT9274 Chemical Structure
BCP10637 KPT9274 1643913-93-2
PAK4-IN-1 is an inhibitor of p21-activated kinases (PAKs), with IC50 of ≤100 nM in MTT assay.
NVS-PAK1-1 Chemical Structure
BCP29548 NVS-PAK1-1 1783816-74-9
NVS-PAK1-1 is a a specific allosteric PAK1 inhibitor.
FRAX597 Chemical Structure
BCP12649 FRAX597 1286739-19-2
FRAX597, a small-molecule pyridopyrimidinone, is a potent and ATP competitive inhibitor of the group I PAKs (PAK1 IC50= 8 nM, PAK2 IC50= 13 nM, PAK3 IC50= 19 nM).
FRAX-1036 Chemical Structure
BCP20209 FRAX-1036 1432908-05-8
FRAX1036 is a novel ATP-competitive small molecule inhibitor of group I p21-activated Kinases (PAKs).
5-Aminosalicylic acid Chemical Structure
BCP05326 5-Aminosalicylic acid 89-57-6
5-Aminosalicylic acid is an anti-inflammatory compound.
FRAX486 Chemical Structure
BCP13764 FRAX486 1232030-35-1
FRAX486 is a selective inhibitor of group I PAKs with IC50s of 8.25/39.5, /55.3 nM for PAK1/PAK2/PAK3 respectivelt; less potent for PAK4(IC50=779 nM).
Fingolimod Chemical Structure
BCP05969 Fingolimod 162359-55-9
Fingolimod(FTY720 free base) is a S1P antagonist with IC50 of 0.033 nM.
Fingolimod HCl Chemical Structure
BCP01808 Fingolimod HCl 162359-56-0
Fingolimod is Src-bcr-Abl Inhibitor & S1P receptor agonist with IC50 of 0.137, 10.98 nM for (S)- and (R)- FTY720-phosphate.
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