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MEK/ERK

Chemical Structure Cat. No. Product Name CAS No.
trans-Zeatin Hydrochloride Chemical Structure
 BCP36686 trans-Zeatin Hydrochloride 6025-81-6
trans-Zeatin Hydrochloride can be used in biological study and therapeutic use for plant-growth factors as cell-proliferating agents for promotion of wound healing.
Urolithin B Chemical Structure
 BCP35736 Urolithin B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
ERK5-IN-2 Chemical Structure
 BCP32587 ERK5-IN-2 1888305-96-1
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.
Longdaysin Chemical Structure
 BCP32583 Longdaysin 1353867-91-0
Longdaysin is a novel inhibitor of CK1, ERK2, and CDK7 kinases.
ASTX-029 Chemical Structure
 BCP32082 ASTX-029 2095719-92-7
ASTX029 is selective Inhibitor of Extracellular Signal-Related Protein Kinases 1 and 2 (ERK 1/2)
JWG-071 Chemical Structure
 BCP31627 JWG-071 2250323-50-1
JWG-071 is the first reported kinase-selective chemical probe for ERK5.
GW284543 Chemical Structure
 BCP31359 GW284543 790186-68-4
GW284543 is a potent and selective MEK5 inhibitor with the potential for cancer treatment.
Methylthiouracil Chemical Structure
 BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
RO5126766 Chemical Structure
 BCP21067 RO5126766 946128-88-7
Ro 5126766 is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively).
TMCB Chemical Structure
 BCP27716 TMCB 905105-89-7
TMCB is a dual-kinase inhibitor. It acts by inhibiting both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8).
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