Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Somatostatin Receptor
- Cholecystokinin Receptor
- Adenylate Cyclase
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Glucagon Receptor
- Adenosine Receptor
- Prostaglandin Receptor
- GnRH Receptor
- NK Receptor
- Leukotriene Receptor
- Glucocorticoid Receptor
- P2 Receptor
- mAChR
- GPR
- CGRP Receptor
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Vasopressin Receptor
- Smoothened/Smo
- Opioid Receptor
- Dopamine Receptor
- mGluR
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Dopamine Receptor
- Opioid Receptor
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- nAChR
- CGRP Receptor
- FAAH
- P2 Receptor
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- Xanthine Oxidase
- ACC
- Mitochondrial Metabolism
- Pyruvate Kinase
- ALDH
- SCD
- Serine Protease
- Neprilysin
- CETP
- FTase
- MLR
- MAGL
- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- NOX
- Elastase
- PAI1
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HCV Protease
- HSP
- Tryptophan Hydroxylase/TPH
- DPP
- Factor Xa
- Procollagen C Proteinase
- Integrase
- Phospholipase
- Phosphodiesterase/PDE
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Azaindazole
- Pyridazine Series
- Nucleoside Series
- Quinoline Series
- Quinazoline
- Pyrazole Series
- Pyrimidine Series
- Boric acid
- Saccharide
- Thiophene Series
- Pyrrole Series
- Indole Series
- Azaindole
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
Mdm2
| Chemical Structure | Cat. No. | Product Name | CAS No. |
|---|
 |
BCP36817 | PROTAC MDM2 Degrader-2 New | 2249944-99-6 |
PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology.
|
|||
 |
BCP31919 | Milademetan tosylate monohydrate New | 2095625-97-9 |
Milademetan (DS-3032b) is a novel potent MDM2 inhibitor that inhibits MDM2-p53 interaction with an IC50 of 5.57 nM in the HTRF assay.
|
|||
 |
BCP23434 | NSC-207895 New | 58131-57-0 |
NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
|
|||
 |
BCP29278 | (?)-Nutlin-3 New | 548472-68-0 |
Nutlin 3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM.
|
|||
 |
BCP10954 | Solasodine | 126-17-0 |
Solasodine is an antioxidant glycoalkaloid of Solanum species.
|
|||
 |
BCP20814 | HDM201 | 1448867-41-1 |
HDM201 is an orally bioavailable human double minute 2 homolog (HDM2) inhibitor with potential antineoplastic activity.
|
|||
 |
BCP25148 | AA-115 | 1818393-16-6 |
AA-115, also known as APG-115, is a highly potent, chemically stable and efficacious MDM2 inhibitor, which has entered clinical development for cancer treatment.
|
|||
 |
BCP10404 | Parthenolide | 20554-84-1 |
Parthenolide is an NF-κB inhibitor, reduces histone deacetylase 1 (HDAC-1) and DNA methyltransferase 1 independent of NF-κB inhibition.
|
|||
 |
BCP17483 | BH3I-1 | 300817-68-9 |
BH3I-1 is a Bcl-2 antagonist. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair.
|
|||
 |
BCP15973 | RO8994 | 1309684-94-3 |
RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2 inhibitor.
|
|||
