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Raw Materials
IDO
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP33269 | LY-3381916 New | 2166616-75-5 |
LY-3381916(IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
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BCP31973 | LM10 New | 1316695-35-8 |
LM10 is a selective TDO inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively)
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BCP20998 | Norharmane New | 244-63-3 |
Norharmane is a potent IDO inhibitor
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BCP09887 | NLG919 | 1402836-58-1 |
GDC-0919, also known as NLG919 and RG6078, is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.
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BCP14546 | Epacadostat | 1204669-58-8 |
Epacadostat is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM.
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BCP16681 | IDO-IN-1 | 914638-30-5 |
IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM).
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BCP24965 | IDO-IN-8 | 1402837-77-7 |
IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.
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BCP26220 | 8-Nitrotryptanthrin New | 77603-42-0 |
8-Nitrotryptanthrin is a potent human indoleamine 2,3-dioxygenase 2 (hIDO2) inhibitor which significantly reduces IDO2 activity with Ki of 0.97 μM.
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BCP17158 | PF-06840003 | 198474-05-4 |
PF-06840003 is a highly selective orally bioavailable IDO-1 inhibitor.
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BCP25760 | Coptisine chloride New | 6020-18-4 |
Coptisine chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM.
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