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Histone Methyltransferase

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Histone Methyltransferase

Chemical Structure Cat. No. Product Name CAS No.
BAY-598 Chemical Structure
BCP37130 BAY-598 1906919-67-2
BAY-598 is selective small molecule inhibitor of SMYD2 with an IC50 of 27 nM.
CPI-1612 Chemical Structure
BCP36917 CPI-1612 2374971-81-8
CPI-1612 is an orally bioavailable EP300/CBP histone acetyltransferase inhibitor
CPI 169 R-enantiomer Chemical Structure
BCP36903 CPI 169 R-enantiomer 1802175-07-0
CPI 169 R-enantiomer is a novel and potent EZH2 inhibitor.
MS1943 Chemical Structure
BCP36892 MS1943 2225938-17-8
MS1943 is a first-in-class, orally bioavailable EZH2 selective degrader. It significantly reduces EZH2 protein levels in numerous triple-negative breast cancer (TNBC) and other cancer and noncancerous cell lines. MS1943 effectively blocks proliferation of multiple TNBC and other cancer cell lines.
EPZ004777 HCl Chemical Structure
BCP36786 EPZ004777 HCl 1380316-03-9
EPZ004777 hydrochloride is the hydrochloride salt of EPZ004777, which is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
GSK2807 Trifluoroacetate Chemical Structure
BCP36148 GSK2807 Trifluoroacetate 2245255-66-5
GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM.
PF-06726304 Chemical Structure
BCP32807 PF-06726304 1616287-82-1
PF-06726304 is a potent and selective EZH2 inhibitor with a Ki of 0.7 nM.
CM-272 Chemical Structure
BCP32745 CM-272 1846570-31-7
CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and DNMTs in hematological malignancies.
Valemetostat Chemical Structure
BCP31915 Valemetostat 1809336-39-7
Valemetostat, also known as DS-3201, is an antineoplastic drug candidate.
A-893 Chemical Structure
BCP31184 A-893 1868232-32-9
A-893 is a cell-active inhibitor of Methyltransferase SMYD2, with an IC50 of 2.8 nM.
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