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HIF

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HIF

Chemical Structure Cat. No. Product Name CAS No.
Rac-PT2399 Chemical Structure
 BCP35881 Rac-PT2399 1672662-07-5
(Rac)-PT2399, the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM.
Acetyl-11-keto-beta-boswellic acid Chemical Structure
 BCP35036 Acetyl-11-keto-beta-boswellic acid 67416-61-9
Acetyl-11-keto-beta-boswellic acid is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
Acriflavine hydrochloride Chemical Structure
 BCP34400 Acriflavine hydrochloride 8063-24-9
Acriflavine is an topical antiseptic agent and has also been used for the treatment of external fungal infections.
SYP-5 Chemical Structure
 BCP34132 SYP-5 1384268-04-5
SYP-5 is a novel HIF-1 inhibitor, suppresses tumor cells invasion and angiogenesis.
PT2399 Chemical Structure
 BCP25901 PT2399 1672662-14-4
PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo.
IDF-11774 Chemical Structure
 BCP31295 IDF-11774 1429054-28-3
IDF-11774 is a potent, orally bioavailable HIF-1 inhibitor.
PT-2385 R-Enantiomer Chemical Structure
 BCP30945 PT-2385 R-Enantiomer 1672666-67-9
PT-2385 is a small molecule inhibitor with oral activity that inhibits hypoxia inducible factor (HIF)-2alpha heterodimerization and its subsequent binding to DNA by binding to HIF-2alpha.
Tilorone dihydrochloride Chemical Structure
 BCP18046 Tilorone dihydrochloride 27591-69-1
Tilorone dihydrochloride is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer, used as an antiviral drug.
KHS101 hydrochloride Chemical Structure
 BCP30178 KHS101 hydrochloride 1784282-12-7
KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3).
KHS101 Chemical Structure
 BCP30177 KHS101 1262770-73-9
KHS-101 is a small molecule that selectively induces a neuronal differentiation phenotype, induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50=1 uM).
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