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GPCR/G Protein

Chemical Structure Cat. No. Product Name CAS No.
ARS-1323-alkyne Chemical Structure
 BCP33669 ARS-1323-alkyne 2436544-27-1
ARS-1323-Alkyne is a novel KRASG12C occupancy probe.
A-3 Hydrochloride Chemical Structure
 BCP37347 A-3 Hydrochloride 78957-85-4
A-3 hydrochloride is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.
TAK 044 Chemical Structure
 BCP37381 TAK 044 157380-72-8
TAK-044 has been found to be an endothelin receptor antagonist that was once studied against some sort of liver disorders and subarachnoid haemorrhage.
JNJ-5207852 Chemical Structure
 BCP37369 JNJ-5207852 398473-34-2
JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively.
Uridine 5'-diphosphoglucose disodium salt Chemical Structure
 BCP37401 Uridine 5'-diphosphoglucose disodium salt 28053-08-9
Uridine 5′-diphosphoglucose disodium salt is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms.
TAK-220 Chemical Structure
 BCP37344 TAK-220 333994-00-6
TAK-220 is an orally bioavailable small-molecule CCR5 antagonist
TAK-220 Hydrochloride Chemical Structure
 BCP37346 TAK-220 Hydrochloride 674782-27-5
TAK-220 is a selective and orally bioavailable CCR5 antagonist.
EST73502 HCl Chemical Structure
 BCP37164 EST73502 HCl 2307458-82-6
EST73502 is a Dual μ?Opioid Receptor Agonist and σ1 Receptor Antagonist Clinical Candidate for the Treatment of Pain.
(S)-PF-04995274 Chemical Structure
 BCP37093 (S)-PF-04995274 2170558-28-6
PF-04995274 is a 5-HT4 receptor partial agonist with Ki = 0.15 - 0.46 nM for 5-HT4 isoforms a, b, d and e, developed for the treatment of Alzheimer's disease (AD).
Ozanimod hydrochloride Chemical Structure
 BCP37091 Ozanimod hydrochloride 1618636-37-5
Ozanimod is a selective sphingosine 1 phosphate receptor modulators and methods which may be useful in the treatment of S1P1-?associated diseases.
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