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Protease/Metabolic Enzyme

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Chemical Structure Cat. No. Product Name CAS No.
Sinogliatin Chemical Structure
BCP31157 Sinogliatin 1191996-10-7
Sinogliatin is a mall molecule glucokinase (GCK; GK) activator.
GKA-50 Chemical Structure
BCP24209 GKA-50 851884-87-2
GKA 50 is a glucokinase activator.
LY2608204 Chemical Structure
BCP02549 LY2608204 1234703-40-2
LY2608204 activates glucokinase with EC50 of 42 nM.
Ro 0281675 Chemical Structure
BCP16457 Ro 0281675 300353-13-3
Ro 28-1675 (Ro 0281675) is a potent allosteric GK activator with a SC1.5 value of 0.24± 0.0019 uM.
AM2394 Chemical Structure
BCP18588 AM2394 1442684-77-6
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.
AMG-3969 Chemical Structure
BCP19926 AMG-3969 1361224-53-4
AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC50 of 4 nM.
MK-0941 mesylate Chemical Structure
BCP25241 MK-0941 mesylate 1137916-97-2
MK-0941 mesylate is a glucokinase activator (GKA) potentially for the treatment of type 2 diabetes. MK-0941 led to improvements in glycemic control that were not sustained. MK-0941 was associated with an increased incidence of hypoglycemia and elevations in triglycerides and blood.
Dorzagliatin Chemical Structure
BCP20539 Dorzagliatin 1191995-00-2
Dorzagliatin is an antidiabetic agent.
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