Classified by application

All Products

Signaling Pathways

Angiogenesis/Protein Tyrosine Kinase
- RET
- Tie2
- DYRK
- DDR
- Ephrin Receptor
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- Integrin
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- JAK
- PDGFR
- BTK
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- FAK
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- EGFR
- c Met
- VEGFR
- FLT3
- c Kit
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Apoptosis Pathway
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Epigenetics
GPCR/G Protein
Hormone Pathay
Ion Channel/Membrane Transporter
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Jak/Stat Pathway
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MAPK Pathway
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Microbiology/Virology
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Neuro Signaling Pathway
NFκB
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PI3K/Akt/mTOR
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Protease/Metabolic Enzyme
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- Integrase
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- Phosphodiesterase/PDE
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TGF beta/Smad
Wnt/Stem Cell
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- BMI1
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- TGFβ/Smad
- Stat
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- Casein Kinase
- JAK
- Notch
- Hedgehog
- Wnt
- Gamma secretase
- GSK3
Others Pathway
- PROTAC
- STING
- Dynamin
- NLR
- AhR
- TLR
- Vitamin D Related
- Autophagy
- LRRK2
- ADC Related
- Interleukin Related
- LpxC
- Others

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

FLT3

Chemical Structure	Cat. No.	Product Name	CAS No.

	BCP36467	UNC2025 hydrochloride New	UNC2025HCL
	UNC-2025 hydrochloride is the hydrochloride salt of UNC-2025, which is the Mer/FLT3 dual inhibitor.

	BCP35054	TG-89 New	936091-56-4
	TG-89 is an inhibitor of JAK2, FLT3, RET and JAK3.

	BCP34471	Crotonoside New	1818-71-9
	Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the treatment of AML.

	BCP34023	Donafenib New	1130115-44-4
	Donafenib is an oral multikinase inhibitor that targets Raf kinase and receptor tyrosine kinases with potential anticancer acivity. Donafenib is under clinical trials in China in patients with advanced hepatocellular carcinoma (HCC).

	BCP23613	FF-10101 New	FF-10101
	FF-10101 is a novel irreversible FLT3 inhibitor, shows excellent efficacy against AML cells with FLT3 mutations

	BCP30180	MRX-2843 New	1429882-07-4
	MRX-2843 is an orally available small-molecule inhibitor of both MERTK and FLT3.

	BCP28052	TG46 New	936091-15-5
	TG-46 is an inhibitor of JAK2, FLT3, RET, JAK3.

	BCP21589	AST-487	630124-46-8
	AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.

	BCP29563	CCT241736	1402709-93-6
	CCT241736 is a novel, orally bioavailable, imidazo[4,5-b]pyridine derivative discovered at our Institute, highly selective for FLT3 and Aurora kinases with an S(10) selectivity score using KINOMEscan? technology of 0.057 (fraction of 386 non-mutant kinases inhibited >90% when screened at 1 uM of CCT241736; San Diego, CA).