Home   >  
Epigenetic Reader Domain

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products






Raw Materials

Epigenetic Reader Domain

Chemical Structure Cat. No. Product Name CAS No.
PROTAC BET Degrader-10 Chemical Structure
BCP36816 PROTAC BET Degrader-10 1957234-97-7
PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, with a DC50 of 49 nM.
SNDX-5613 Chemical Structure
BCP36044 SNDX-5613 2169919-21-3
SNDX-5613 is a potent and specific Menin-MLL inhibitor. It can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
MI-463 Chemical Structure
BCP36072 MI-463 1628317-18-9
MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.
MI-538 Chemical Structure
BCP36073 MI-538 1857417-10-7
MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM.
GSK620 Chemical Structure
BCP35923 GSK620 2088410-46-0
GSK620 is a novel BD2-selective BET inhibitor in vivo tool , binding to the individual tandem bromodomains [BD1 and BD2] of BRD2, BRD3, BRD4, and BRDT.
GSK046 Chemical Structure
BCP35924 GSK046 2474876-09-8
GSK046 (iBET-BD2) is a selective and orally active inhibitor of BET, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively.
BRD4 Inhibitor-10 Chemical Structure
BCP35872 BRD4 Inhibitor-10 1660117-38-3
BRD4 Inhibitor-10 is a potent and selective BET inhibitor with IC50 of 5 nM and 41 nM for the binding of BRD4-BD1 and BRD4-BD2 to acetylated histones, respectively. BI 894999 is highly selective for BRD2/3/4 and BRDT (Kd of 0.49-1.6?nM), with at least a 200-fold selectivity vs. BRD4-BD1.
M-89 Chemical Structure
BCP35588 M-89 2363165-42-6
M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia.
Y06036 Chemical Structure
BCP35043 Y06036 1832671-96-1
Y06036 is a potent and selective BET inhibitor, which binds to the BRD4(1) bromodomain with Kd value of 82 nM. Antitumor activity.
MS31 Chemical Structure
BCP34903 MS31 2366264-12-0
MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3. It is not toxic to nontumorigenic cells.
123下一頁末頁共 110 條記錄 1 / 11 頁 
福建36选7奖金 广西麻将烂牌怎么打 篮网球azn比分直播 天津11选5走势图表 青海快三另类投注技巧 四川快乐12今天开奖结 四个好友麻将 网上棋牌赌钱必赢法 麻将血流成河换三张技巧 体彩飞鱼口诀 天天赢棋牌 未来陕西麻将代理微信 彩金捕鱼ol红包版 河南体彩十一选五开奖走势 云南快乐十分组三遗漏 极速赛车全天计划数据 二人麻将技巧口诀