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Chemical Structure Cat. No. Product Name CAS No.
VUF11207 fumarate Chemical Structure
BCP34887 VUF11207 fumarate 1785665-61-3
VUF11207 fumarate is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7.
ALX 40-4C Chemical Structure
BCP34188 ALX 40-4C 143413-49-4
ALX 40-4C is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.
NBI-74330 Chemical Structure
BCP34091 NBI-74330 855527-92-3
NBI-74330 is a small molecule antagonist for CXCR3
USL311 Chemical Structure
BCP33234 USL311 1373268-67-7
USL311 is a selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4.
Mavorixafor trihydrochloride Chemical Structure
BCP26048 Mavorixafor trihydrochloride 880549-30-4
Mavorixafor is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.
BX471 hydrochloride Chemical Structure
BCP32594 BX471 hydrochloride 288262-96-4
BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
SX-682 Chemical Structure
BCP32154 SX-682 1648843-04-2
SX-682 is a potent and selective Cxcr1/2 inhibitor potentially useful for castration-resistant prostate cancer. CXCR1 and CXCR2 chemokine receptors and their ligands (CXCL1/2/3/7/8) play an important role in tumor progression.
JMS-17-2 Chemical Structure
BCP31312 JMS-17-2 1380392-05-1
JMS-17-2 is a potent and selective antagonist of CX3CR1.
Elubrixin hydrochloride Chemical Structure
BCP23554 Elubrixin hydrochloride 688763-65-7
Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist, which is potentially useful for Inflammatory bowel disease therapies.
Baohuoside I Chemical Structure
BCP30977 Baohuoside I 113558-15-9
Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.
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