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Chemical Structure Cat. No. Product Name CAS No.
CP154526 Chemical Structure
BCP26372 CP154526 157286-86-7
CP 154,526 is a selective, non-peptide CRF1 receptor antagonist (Ki values are 2.7 and > 10000 nM for CRF1 and CRF2 receptors respectively).
Verucerfont Chemical Structure
BCP26371 Verucerfont 885220-61-1
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively.
CP 376395 Chemical Structure
BCP28957 CP 376395 175140-00-8
CP-376395 is a CRF1-selective antagonist.
CP 376395 hydrochloride Chemical Structure
BCP28958 CP 376395 hydrochloride 1013933-37-3
CP 376395 hydrochloride is a potent and selective CRF-RI receptor antagonist (Ki value are 12 and >10000 nM for CRF-RI and CRF-RII receptors respectively).
R-121,919 Chemical Structure
BCP23964 R-121,919 195055-03-9
R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.
Pexacerfont Chemical Structure
BCP26369 Pexacerfont 459856-18-9
Pexacerfont is a selective corticotropin-releasing factor (CRF1) receptor antagonist with IC50 of 6.1±0.6 nM for human CRF1 receptor.
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