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Chemical Structure Cat. No. Product Name CAS No.
Prexasertib dimesylate Chemical Structure
BCP35489 Prexasertib dimesylate 1234015-58-7
Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM.
V158411 Chemical Structure
BCP25319 V158411 1174664-88-0
V158411 is a novel selective Chk1 inhibitor.
LY2880070 Chemical Structure
BCP32047 LY2880070 1375637-35-6
LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy. CHK1 is a serine/threonine kinase.
CCT241533 Chemical Structure
BCP21396 CCT241533 1262849-73-9
CCT241533 is a potent and selective Inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors.
GDC0575 hydrochloride Chemical Structure
BCP30767 GDC0575 hydrochloride 1196504-54-7
GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2?nM.
GDC-0575 dihydrochloride Chemical Structure
BCP29768 GDC-0575 dihydrochloride 1657014-42-0
GDC-0575 dihydrochloride is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
SAR-020106 Chemical Structure
BCP29578 SAR-020106 1184843-57-9
SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50 of 13.3 nM.
AZD7762 HCl Chemical Structure
BCP25387 AZD7762 HCl 1246094-78-9
AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and potentiating DNA-targeted therapies.
GDC-0575 Chemical Structure
BCP20675 GDC-0575 1196541-47-5
GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2?nM.
Prexasertib Mesylate Hydrate Chemical Structure
BCP24330 Prexasertib Mesylate Hydrate 1234015-57-6
Prexasertib is a Chk1 inhibitor potentially for the treatment of ovarian cancer and breast cancer.
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