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CGRP Receptor

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CGRP Receptor

Chemical Structure Cat. No. Product Name CAS No.
BIBN 4096BS Chemical Structure
BCP29403 BIBN 4096BS 204697-65-4
BIBN 4096BS is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP.
BMS 927711 Chemical Structure
BCP28575 BMS 927711 1289023-67-1
Rimegepant is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.
MK-8031 Chemical Structure
BCP29018 MK-8031 1374248-81-3
MK-8031, also known as Atogepant, is a calcitonin gene-related peptide receptor antagonist.
MK-3207 HCl Chemical Structure
BCP27622 MK-3207 HCl 957116-20-0
MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.
Telcagepant Chemical Structure
BCP07257 Telcagepant 781649-09-0
MK-0974 is a highly potent, selective, and orally bioavailable CGRP receptor antagonist, which may be valuable in the acute treatment of migraine.
MK 3207 Chemical Structure
BCP02225 MK 3207 957118-49-9
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist. In common with other CGRP receptor antagonists, MK-3207 displays lower affinity for human CGRP receptors from other species, including canine and rodent.
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