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CDK

Chemical Structure Cat. No. Product Name CAS No.
BSJ-03-123 Chemical Structure
BCP36852 BSJ-03-123 2361493-16-3
BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
PROTAC CDK9 Degrader-1 Chemical Structure
BCP36814 PROTAC CDK9 Degrader-1 2118356-96-8
PROTAC CDK9 Degrader-1 is a selective CDK9 degrader.
THAL-SNS-032 Chemical Structure
BCP36024 THAL-SNS-032 2139287-33-3
THAL-SNS-032 is a selective CDK9 degrader. THAL-SNS-032 consists of a CDK-binding SNS-032 ligand linked to a thalidomide.
AZD4573 Chemical Structure
BCP35769 AZD4573 2057509-72-3
AZD4573 is a potent and highly selective CDK9 inhibitor (IC50 of <4 nM) that enables transient target engagement for the treatment of hematologic malignancies.
(±)-BAY-1251152 Chemical Structure
BCP33292 (±)-BAY-1251152 1610358-53-6
(±)-BAY-1251152 is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor.
Trilaciclib dihydrochloride Chemical Structure
BCP25727 Trilaciclib dihydrochloride 1977495-97-8
Trilaciclib 2HCl is a CDK4/6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively.
JSH-150 Chemical Structure
BCP33243 JSH-150 2247481-21-4
JSH-150 is a potent CDK9 inhibitor.
Alsterpaullone Chemical Structure
BCP33241 Alsterpaullone 237430-03-4
Alsterpaullone, also known as 9-Nitropaullone and NSC 705701, is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3β (GSK3β).
SR-4835 Chemical Structure
BCP33214 SR-4835 2387704-62-1
SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death.
 Chemical Structure
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