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Cathepsin

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Cathepsin

Chemical Structure Cat. No. Product Name CAS No.
LHVS Chemical Structure
 BCP34916 LHVS 170111-28-1
LHVS is an irreversible cysteine protease cathepsin S (CatS) inhibitor.
CA-074 ME Chemical Structure
 BCP10805 CA-074 ME 147859-80-1
CA-074 methyl ester is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects.
Calpeptin Chemical Structure
 BCP34012 Calpeptin 117591-20-5
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets. Calpeptin is also an inhibitor of cathepsin K.
NSC 185058 Chemical Structure
 BCP30689 NSC 185058 39122-38-8
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. NSC185058 markedly attenuates autophagic activity.
Petesicatib Chemical Structure
 BCP30532 Petesicatib 1252637-35-6
Petesicatib is a cathepsin inhibitor drug candidate.
Z-Phe-Tyr(tBu)-diazomethylketone Chemical Structure
 BCP29942 Z-Phe-Tyr(tBu)-diazomethylketone 114014-15-2
Z-Phe-Tyr(tBu)-diazomethylketone is an irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.
Z-Gly-Leu-Phe-CMK Chemical Structure
 BCP23532 Z-Gly-Leu-Phe-CMK Z-Gly-Leu-Phe-CMK
Z-Gly-Leu-Phe-CMK is a cathepsin G inhibitor.
Balicatib Chemical Structure
 BCP09098 Balicatib 354813-19-7
Balicatib, an inhibitor of the osteoclastic enzyme cathepsin K.
Leupeptin hemisulfate anhydrous Chemical Structure
 BCP10660 Leupeptin hemisulfate anhydrous 103476-89-7
Leupeptin is a reversible inhibitor of protease with Ki values of 35 nM, 3.4 μM, 6 nM and 72 nM for bovine trypsin, human plasmin, bovine spleen cathepsin B and recombinant human calpain, respectively.
Calpain Inhibitor III Chemical Structure
 BCP15636 Calpain Inhibitor III 88191-84-8
MDL 28170 is a selective inhibitor, which inhibites calpain with Ki values of 10nM and cathepsin B with Ki values of 25 nM while does not inhibit trypsin-like serine proteases.
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