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Chemical Structure Cat. No. Product Name CAS No.
Zamicastat Chemical Structure
BCP33811 Zamicastat 1080028-80-3
Zamicastat is a dopamine β-hydroxylase (DBH) inhibitor that could cross the blood-brain barrier (BBB) and cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8?μM and 17.0?μM, respectively. Reduces high blood pressure.
ML753286 Chemical Structure
BCP25916 ML753286 1699720-89-2
ML753286 is a potent inhibitor for BCRP, ML753286 has low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species.
Brevianamide F Chemical Structure
BCP24252 Brevianamide F 38136-70-8
Brevianamide F is a naturally occurring 2,5-diketopiperazine that possess interesting breast cancer resistance protein (BCRP) inhibitory activity.; also shows agonism towards Ca(2+)-channel activity at 100 uM, and has potentiation for use in the treatment of cardiovascular dysfunction.
YHO-13177 Chemical Structure
BCP28922 YHO-13177 912287-56-0
YHO-13177 is a potent and specific inhibitor of breast cancer resistance protein (BCRP/ABCG2).
KS 176 Chemical Structure
BCP17744 KS 176 1253452-78-6
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
YHO-13351 (free base) Chemical Structure
BCP28919 YHO-13351 (free base) 912288-64-3
YHO-13351 (free base) is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP.
YHO-13351 Chemical Structure
BCP28920 YHO-13351 1346753-00-1
YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP.
Fumitremorgin C Chemical Structure
BCP28921 Fumitremorgin C 118974-02-0
Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor.
Elacridar Chemical Structure
BCP05709 Elacridar 143664-11-3
Elacridar is a P-glycoprotein and breast cancer resistance protein inhibitor that has been used to improve the brain distribution of drugs that are substrates of P-gp and BCRP.
Elacridar HCl Chemical Structure
BCP14056 Elacridar HCl 143851-98-3
Elacridar Hcl (GF120918; GW0918) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules.
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