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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
Ac-YVAD-CMK Chemical Structure
BCP37297 Ac-YVAD-CMK 178603-78-6
Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1).
iFSP1 Chemical Structure
BCP37001 iFSP1 150651-39-1
iFSP1 is a ferroptosis suppressor protein 1 (FSP1) inhibitor and ferroptosis inducer.
PROTAC MDM2 Degrader-2 Chemical Structure
BCP36817 PROTAC MDM2 Degrader-2 2249944-99-6
PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology.
Bcl-2-IN-2 Chemical Structure
BCP36375 Bcl-2-IN-2 2383085-86-5
Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL.
BCL2 Degrader C5 Chemical Structure
BCP36383 BCL2 Degrader C5 2378801-85-3
BCL2 Degrader C5 is a novel potent and selective degrader of Bcl-2.
Marinopyrrole A Chemical Structure
BCP36069 Marinopyrrole A 1227962-62-0
Marinopyrrole A is a novel and specific Mcl-1 inhibitor with an IC50 value of 10.1 μM, and shows >8 fold selectivity than BCL-xl (IC50 > 80 μM).
PD-1/PD-L1 Inhibitor 3 Chemical Structure
BCP35838 PD-1/PD-L1 Inhibitor 3 1629654-95-0
PD-1/PD-L1 Inhibitor 3 is a Macrocyclic inhibitor of PD-1/PD-L1 interaction with IC50 of 5.6 nM.
AUNP-12 TFA Chemical Structure
AUNP-12 TFA is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions.
YM-155 hydrochloride Chemical Structure
BCP35549 YM-155 hydrochloride 355406-09-6
YM155 is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM.
RIPK1-IN-4 Chemical Structure
BCP35149 RIPK1-IN-4 1481641-08-0
RIPK1-IN-4 is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase.
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