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Antibodies

Chemical Structure Cat. No. Product Name CAS No.
Edrecolomab Chemical Structure
BCP36542 Edrecolomab 156586-89-9
Edrecolomab is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A), which is expressed on epithelial tissues and on various carcinomas.
Trastuzumab deruxtecan Chemical Structure
BCP36537 Trastuzumab deruxtecan 1826843-81-5
Trastuzumab deruxtecan is an antibody-drug conjugate that includes a human epidermal growth factor receptor 2 (HER2)-directed antibody trastuzumab and a topoisomerase I inhibitor conjugate deruxtecan (a derivative of exatecan).
Alirocumab Chemical Structure
BCP25199 Alirocumab 1245916-14-6
Alirocumab is a human monoclonal antibody to PCSK9 (proprotein convertase subtilisin/kexin type 9), a circulating protein that modulates the activity of the LDL cholesterol receptor in the liver. The monoclonal antibody lowers serum LDL cholesterol and is used to treat severe hypercholesterolemia. Alirocumab therapy has been associated with a low rate of serum aminotransferase elevations and has yet to be linked to instances of clinically apparent acute liver injury.
Tislelizumab Chemical Structure
BCP35899 Tislelizumab Tislelizumab
Tislelizumab (BGB-A317) is a humanized monoclonal antibody directed against PD-1. It prevents PD-1 from binding to the ligands PD-L1 and PD-L2 (hence it is a checkpoint inhibitor). It is being investigated as a treatment for advanced solid tumors.
Ramucirumab Chemical Structure
BCP26258 Ramucirumab 947687-13-0
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D.
Vedolizumab Chemical Structure
BCP26256 Vedolizumab 943609-66-3
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.
Ozanezumab Chemical Structure
BCP23507 Ozanezumab 1310680-64-8
Ozanezumab is a monoclonal antibody.
Sacituzumab govitecan Chemical Structure
BCP28938 Sacituzumab govitecan 1491917-83-9
Sacituzumab Govitecan is an antibody drug conjugate containing the humanized monoclonal antibody, hRS7, against tumor-associated calcium signal transducer 2 (TACSTD2 or TROP2) and linked to the active metabolite of irinotecan, 7-ethyl-10-hydroxycamptothecin (SN-38), with potential antineoplastic activity.
Sarilumab Chemical Structure
BCP31891 Sarilumab 1189541-98-7
Sarilumab is a human monoclonal antibody against the interleukin-6 receptor.
Evolocumab Chemical Structure
BCP25203 Evolocumab 1256937-27-5
Evolocumab is a monoclonal antibody designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver surface. In the absence of PCSK9, there are more LDL receptors on the surface of liver cells to remove LDL-C from the blood.
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