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AKT

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AKT

Chemical Structure Cat. No. Product Name CAS No.
Merck-22-6 Chemical Structure
 BCP36078 Merck-22-6 612847-42-4
Merck-22-6 is an allosteric dual Akt1, Akt2 inhibitor.
Urolithin B Chemical Structure
 BCP35736 Urolithin B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
Recilisib sodium Chemical Structure
 BCP35048 Recilisib sodium 922139-31-9
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
E-Guggulsterone Chemical Structure
 BCP34834 E-Guggulsterone 39025-24-6
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii.
(Z)-Guggulsterone Chemical Structure
 BCP07472 (Z)-Guggulsterone 39025-23-5
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Miransertib HCl Chemical Structure
 BCP25709 Miransertib HCl 1313883-00-9
Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.
Ipatasertib dihydrochloride Chemical Structure
 BCP23821 Ipatasertib dihydrochloride 1396257-94-5
Ipatasertib dihydrochloride is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
Recilisib Chemical Structure
 BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
AT7867 dihydrochloride Chemical Structure
 BCP30936 AT7867 dihydrochloride 1431697-86-7
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
LM22B-10 Chemical Structure
 BCP30139 LM22B-10 342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
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